Mitou Shoukan://Blood-Sign - Volume 3, Opening X-01 - Let’s Settle This Once and For All

In the 900th millennium of humanity's journey towards the Star Sea, the unstoppable Expeditionary Army dominates the universe, and the fiery Age of Great Expansion nears its conclusion.Ancient cultivators seize mythology in pursuit of becoming sacred Buddhas; the new generation of prodigies shatter shackles, yearning to surpass limits!Yet, in a secluded corner of the vast cosmos, Qin Shi chooses to grind through countless achievements, unlocking one monument after another.Until reaching the pinnacle of evolution, the ultimate summit!

She was the head of a powerful, medicine-orientated aristocratic family.

Crossing through a millennium, she ended up in the body of the General Household’s “trash” young miss, whose engagement with the Crown Prince was just broken as she suffered under everybody’s taunts!

In the drafting feast, she was re-engaged by the Emperor to marry the famous disabled prince!

Everybody laughed, a blind trash with a disabled wastrel. What a perfect match!

However, they didn’t know that in her hand, she grasped the long-lost primordial pill recipes! Her practice in medicine had reached the apex! Her contracted beasts were unique in the world!

What was the most frightening, was the disabled prince she was engaged to…….

A black-belly full of dirty tricks, with a heaven-opposing cultivation physique, he defeats all geniuses!

In his wheelchair during the day, yet entangling her in bed as he trained his waist muscles… MF! Is he really crippled!?

- Description from Novelupdates

Others treated disease to save person, he treated disease to steal heart.

The Frost Goddess was deeply captivated by him. The gentle and kind beautiful teacher was completely enchanted by him. Even the cold and beautiful female assassin melted quietly because of him.

Competing in medical skills? He was the one who treated the Godly Doctor. Competing with backgrounds? Leaders rushed to him. What? You actually wanted to compete with him in a match for match? Looking at the gentle girl beside him, Tang Yu had a headache as he said, “Beautiful girl, how did you fall in love with me?”

- Description from Novelupdates

After rebirth, Long Xiaoyuan went into raptures because he was in poor health in his previous life. However, he suddenly found that his soul was in the body of a fatuous and self-indulgent emperor.